A response to environmental stress such as persistent exposure to the sun, smoking, or taking a medication that can cause your skin to darken or spot, called, It could be an indicator of an underlying medical condition like. The mucosal melanotic macule is a variant of simple lentigo that is located on mucosal surfaces, in particular the lower lip. Topics A–Z Multiple causes are known, and they may range from simple iatrogenic mechanisms, such as implantation of dental amalgam, to complex medical disorders, such as Peutz-Jeghers syndrome. Labial melanotic macule. For most of the melanotic macule your dermatologist or physician will observe it over time to make sure that it does not change in shape, color, or texture and will not remove it and it will not need any treatment. If a child has one it is usually because of their race. A labial melanotic macule is thought to be provoked by sun exposure, and it is more common in fair-skinned people. Their etiology is not clear and it may represent a physiologic or reactive process. As most melanotic macule is benign for women they may be able to hide them under makeup if they are light in color and small enough so they do not attract any attention. H Arch Dermatol. If the melanotic macule is removed it can create a small scar or depression in the tissue which may or may not be noticeable. See smartphone apps to check your skin. A dermatologist can evaluate a melanotic macule to determine if it poses any health risks to the patient. Size ranges from 1–8 mm. The average age of presentation is 43 years, with a female predilection. Melanotic macules are benign pigmented lesions that are found in the oral cavity, caused by an increase in pigmentation in the basal cell layer of the epithelium and the lamina propria. On the penis in men (penile melanotic macule, a penile lentigo). Melanin pigmentation tends to be present in significant amounts in the basal-cell layer and less often in the lamina propria. 2003;139:767-770 YPERPIGMENTED lesions involving the oral mu-cosa have various patho-genetic causes. What causes an oral melanotic macule? Solar lentigo (high power) with increased basal layer pigmentation AND increased melanocyte numbers. Luckily, melanotic macules are harmless. A number of inherited diseases are manifested by pigmented oral lesions. HYPERPIGMENTED lesions involving the oral mucosa have various pathogenetic causes. Multiple lentiginosis (various syndromes including. Some of the possible causes of Hypermelanotic macule or similar disorders may include: 2. Ephelis (freckle) is a circumscribed brown macule over skin that has been exposed to sunlight. Hence, treatment is not required. If a person decides that they do want them removed this can be done by: Pictures collection of the condition Melanotic Macule…, 35 Most Frequently Asked Questions About Coronavirus (COVID-19) – (with references). This medical condition is a dark spot that is usually found on your lips, usually the bottom one but can appear on the top lip also. 7,8 NAME syndrome– a … Labial melanotic macule causes Labial melanotic macule is thought to be provoked by sun exposure, and it is more common in fair skinned people. Brown macules on the lower lip are relatively common, especially in young adult women. It is also sometimes called a labial lentigo and when multiple lesions are present, mucosal melanosis. Lesions can also be found in the mouth (oral melanotic macule), on the vulva (vulval labial melanotic macule; vulval melanosis) or on the penis (penile melanotic macule). » Similar freckles may also occur in areas that are not exposed to the sun: Labial melanotic macules do not cause any symptoms but their appearance can be a concern to the patient. Oral Melanotic Macule identifiable etiologic factor, the term oral melanotic macule has been suggested2. It is suggested that the term oral melanotic macule be used for these lesions, unless a specific cause can be confirmed by clinical data. Conclusion: The congenital lingual melanotic macule represents a clinically distinct, benign, pigmented oral melanoticlesion,andmaybemorecommonthanthelit-erature suggests. To make sure what type of treatment is needed, if any, they will usually do a skin biopsy to confirm if it is melanotic macule or another medical condition that could be precancerous or cancerous. The color of the lesion is normally darker than the tissue that surrounds it. Being born with one or having it appear in early childhood, which is common for people who have dark skin. Last reviewed by Dr. Raj MD on August 14th, 2018. The etiology is not clear and it may represent a physiologic or reactive process. [Congenital melanotic macules of the tongue] If you have any concerns with your skin or its treatment, see a dermatologist for advice. They may be more common than the literature suggests, especially among dark-skinned subjects. » This dark area could be a melanotic macule, which is a noncancerous dark patch on the skin — called hyperpigmentation — of a mucous membrane. However it may also occur in dark-skinned individuals and, as described above, similar lesions can arise in sites that are never sun-exposed. These are Genetic disorders and Lichen sclerosis. A mucosal melanocytic macule is a well-defined, oval, brown to black, flat patch, usually found on the lip (a labial melanocytic macule). When these macules occur in isolation, they are usually sporadic and no associated conditions are observed. Oral melanotic macules can appear in people of any age, of any race, and of either sex. 6 Biopsy for routine histopathologic examination is recommended to rule out oral melanoma in patients with melanotic macule on the palate, where malignant melanoma is most prevalent. GENETIC CAUSES. Author: Dr Mark Duffill, Dermatologist, Hamilton, New Zealand, 2008. If it is irregular in shape or big it could be noticeable if removed. Excision can also be performed but will leave a scar. However, we know that it is due to over-production and accumulation of melanin within the tissues. They can occasionally have an irregular edge and there may be a history of colour change which can cause confusion with other pigmented lesions, including melanoma. Melanin is a normal skin pigment that gives the skin its darker color. Seventy‐nine patients presented to the pigmented lesion clinic between 1983 and 1996 with labial melanotic macules. Having a melanotic macule does not cause any symptoms but when you see one it is usually smaller than seven millimeters in diameter. Melanotic Macule Causes There is a variety of causes for a person to have a melanotic macule. Another name for this medical condition is labial melanotic macule and it is sometimes referred to as a freckle on the lip. DermNet provides Google Translate, a free machine translation service. Although it can appear at any age in either sex, race, or gender, it is most commonly found in people who are dark skinned and in their middle ages and are female. Sponsored content: melanomas are notoriously difficult to discover and diagnose. Shen ZY, Liu W, Bao ZX, Zhou ZT, Wang LZ Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2011 Jul;112(1):e21-5. doi: 10.1016/j.tripleo.2011.02.040. Labial melanotic macule (low power); mild acanthosis without elongation of rete ridges. According to RDH Magazine, this common oral condition is present in 3 percent of the general population and is caused by a … Usually solitary, a labial melanotic macule is most commonly seen in adult women but it also occurs in males and in young people. Some of the rare genetic disorders associated with this condition include the following: 1. The oral melanotic macule (MM) is a small, well-circumscribed brown-to-black macule that occurs on the lips and mucous membranes. Lichen sclerosis – a skin disease which is characterized by white patches while are usually thinner than normal skin Some linked genetic disorders may include: 1. DermNet NZ does not provide an online consultation service. Objective: Our purpose was to define the clinical, histologic, immunohistochemical, and electronmicroscopic features of genital melanotic macules. There is a variety of causes for a person to have a melanotic macule. Genetic disorders 2. Mucosal melanotic macule is a broader term encompassing lesions of the mouth as well as the lip. These conditions can be differentiated from labial melanotic macule by a combination of clinical and histological features. Simple lentigo — Simple lentigines often appear during childhood as sharply circumscribed, round-to-oval, uniformly brown or … What is the cause of labial melanotic macule? Gupta G, Williams REA, Mackie RM. Background: Genital melanotic macules are poorly recognized lesions, which appear as isolated discrete macules. Currently, there is no specific cause for this vulvar benign but there are some rarely linked factors. The exact cause for VM is unknown currently. Typical lesions can just be observed. 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